The New Orleans Saints will try to continue their success at home when they host the Los Angeles Chargers on Monday Night Football. It’s the second-to-last game of the Week 5 NFL schedule. The Saints (2-2), who won the NFC South at 13-3 in 2019, are 7-3 at home since the start of last season. Los Angeles, which finished fourth in the AFC West at 5-11 a year ago, is 4-6 on the road since last September. Los Angeles will be without running back Austin Ekeler (hamstring), while New Orleans will be without star wideout Michael Thomas. New Orleans won the last meeting with Los Angeles, a 35-34 victory in 2016 at San Diego.
Kickoff from the Superdome is set for 8:15 p.m. ET. New Orleans is a seven-point favorite in the latest Saints vs. Chargers odds from William Hill after the line opened at